PEER-REVIEWED PUBLICATIONS
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Initiating Protein Synthesis with Noncanonical Monomers In Vitro and In Vivo
J.M. Tharp,* J.A. Walker,* D. Söll, A. Schepartz
Method. Enzymol. 2021, (In press).
Genetic Encoding of Three Distinct Noncanonical Amino Acids Using Reprogrammed Initiator and Nonsense Codons
J.M. Tharp, O. Vargas-Rodriguez, A. Schepartz, D. Söll
ACS Chem. Biol. 2021, 16, 766–774.
An Amber Obligate Active Site-Directed Ligand Evolution Technique for Phage Display
J.M. Tharp,* J.T. Hampton,* C.A. Reed,* A. Ehnbom, P.-H.C. Chen. J.S. Morse, Y. Kurra, L.M. Pérez, S. Xu, W.R. Liu
Nature Commun. 2020, 11, 1392.
Hijacking Translation Initiation for Synthetic Biology
J.M. Tharp,* N. Krahn,* U. Varshney, D. Söll
ChemBioChem, 2020, 21, 1287–1396.
Selected as a Very Important Paper (VIP)
Initiation of Protein Synthesis with Non-Canonical Amino Acids In Vivo
J.M. Tharp, O. Ad, K. Amikura, F.R. Ward, E. Garcia, J.H.D. Cate, A. Schepartz, D. Söll
Angew. Chem. Int. Ed. 2020, 59, 3122-3126.
Engineering Aminoacyl-tRNA Synthetases for Use in Synthetic Biology
N. Krahn,* J.M. Tharp,* A. Crnković,* D. Söll
The Enzymes, 2020, 48, 351–359.
A Genetically Encoded Phage-Displayed Cyclic-Peptide Library
X.S. Wang, P.S.C. Chen, J.T. Hampton, J.M. Tharp, C.A. Reed, S.K. Das, D.S. Wang, H.S. Hayatshahi, Y. Shen, J. Liu, W.R. Liu
Angew. Chem. Int. Ed. 2019, 131, 16061-16056.
Using Amber and Ochre Nonsense Codons to Code Two Different Noncanonical Amino Acids in One Protein Gene
J.M. Tharp, W.R. Liu
Methods Mol. Biol. 2018, 1728, 147-154.
tRNAPyl: Structure, Function, and Applications
J.M. Tharp, A. Ehnbom, W.R. Liu
RNA Biol. 2018, 15, 441-452.
Genetic Code Expansion: Synthetases Pick Up the PACE
J.M. Tharp, W.R. Liu
Nat. Chem. Biol. 2017, 13, 1205-1206.
A Genetically Encoded Allysine for the Synthesis of Proteins with Site-Specific Lysine Dimethylation
Z.A. Wang, Y. Kurra, X. Wang, J.M. Tharp, E.C. Vatansever, W.W. Hsu, S. Dai, X. Fang, W.R. Liu
Angew. Chem. Int. Ed. 2016, 56, 212-216.
Genetically Encoded Fluorophenylalanines Enable Insights Into the Recognition of Lysine Trimethylation by an Epigenetic Reader
Y.J. Lee, M.J. Schmidt, J.M. Tharp, A. Weber, H. Zheng, J. Gao, M.L. Waters, D. Summerer, W.R. Liu
Chem. Commun. 2016, 52, 12606-12609.
The "π-Clamp" Offers a New Strategy for Site-Selective Protein Modification
J.M. Tharp, W.R. Liu
ChemBioChem 2016, 17, 883-885.
Expanding the Chemical Diversity of Lasso Peptide MccJ25 with Genetically Encoded Non-Canonical Amino Acids
F.J. Piscotta, J.M. Tharp, W.R. Liu, J.A. Link
Chem. Commun. 2015, 51, 409-412.
Genetic Incorporation of Seven Ortho-Substituted Phenylalanine Derivatives
J.M. Tharp, Y.S. Wang, Y.J. Lee, Y.Y. Yang, W.R. Liu
ACS Chem. Biol. 2014, 9, 884-890.
Pyrrolysyl-tRNA Synthetase: An Ordinary Enzyme but an Outstanding Genetic Code Expansion Tool
W. Wan, J.M. Tharp, W.R. Liu
Biochim. Biophys. Acta 2014, 1844, 1059-1070.
Developmental Plasticity of Thermal Tolerances in Temperate and Subtropical Populations of Drosophila melanogaster
B.S. Cooper, J.M. Tharp, I.I. Jernberg, M.J. Angilletta
J. Therm. Biol. 2012, 37, 211-216.
* signifies equal author contribution
